Alternative Medications for Anxiety

"Clonidine and guanfacine are alpha-2 receptor agonists that decrease sympathetic outflow from the central nervous system. Posttraumatic stress disorder (PTSD) is an anxiety disorder that is theorized to be related to a hyperactive sympathetic nervous system. " source

"Propranolol is a beta-adrenergic antagonist that is FDA-approved for multiple indications including hypertension, angina, atrial fibrillation and arrhythmias, migraine prophylaxis, and essential tremor (77). Although it is not approved for any psychiatric indications, it has been widely prescribed for SAD and performance anxiety. There is, however, a lack of research support for the use of propranolol in anxiety disorders (77) although it may still have a role in certain task-specific anxieties (78). " source

Buspar (Buspirone): "This medication is used to treat anxiety. It may help you think more clearly, relax, worry less, and take part in everyday life. It may also help you to feel less jittery and irritable, and may control symptoms such as trouble sleeping, sweating, and pounding heartbeat. Buspirone is a medication for anxiety (anxiolytic) that works by affecting certain natural substances in the brain (neurotransmitters)." source

Vistaril (Hydroxyzine) source

"Your doctor may prescribe Vistaril as a short-term treatment for anxiety or as an alternative to other habit-forming anxiety medications, such as benzodiazepines. If you have combined allergies and anxiety, this medication may also be a good choice. Vistaril is not a good choice for long-term treatment of anxiety, as it has not been shown to be effective for this use." source

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